About   Help   FAQ
Tg(Myh6-Ppp3ca)37Eno
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Ppp3ca)37Eno
Name: transgene insertion 37, Eric N Olson
MGI ID: MGI:3056186
Synonyms: alpha-MHC-CnA*, CalTG, CN, CNA, MHC-CnA
Transgene: Tg(Myh6-Ppp3ca)37Eno  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Constitutively active, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Ppp3ca)37Eno expresses 1 gene
 
Mutation detailsThe promoter region of Myh6 drives expression of a constitutively active Ppp3ca cDNA in cardiomyocytes. This is a representative record representing Tg46, Tg22, Tg110, Tg106, Tg108, Tg41, Tg37, and Tg39 which vary in the number of copies of the transgene integrated but all have identical phenotypes. (J:93176)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:93176 Molkentin JD, et al., A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 1998 May 17;93(2):215-28
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/20/2020
MGI 6.16
The Jackson Laboratory