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Dand5tm1Belo
Targeted Allele Detail
Nomenclature
Symbol: Dand5tm1Belo
Name: DAN domain family member 5, BMP antagonist; targeted mutation 1, Jose Antonio Belo
MGI ID: MGI:3056132
Synonyms: cerl-2-
Gene: Dand5  Location: Chr8:84815405-84832265 bp, - strand  Genetic Position: Chr8, 41.17 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93051
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P/Ola
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe second exon was replaced with a lacZ cassette and a neomycin-resistance gene. In situ hybridization demonstrated that lacZ was expressed in heterozygotes. (J:93051)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dand5 Mutation:  13 strains or lines available
References
Original:  J:93051 Marques S, et al., The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 2004 Oct 1;18(19):2342-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory