About   Help   FAQ
rda
Spontaneous Allele Detail
Nomenclature
Symbol: rda
Name: roundabout
MGI ID: MGI:3055794
Synonyms: vertigo, vto
Gene: rda  Location: unknown  Genetic Position: Chr9, Syntenic
Cochlear hair cell abnormalities in rda/rda and Elmod1rda-2J/Elmod1rda-2J mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Intergenic deletion
  rda involves 2 genes/genome features (Elmod1, Tnfaip8l3) View all
 
Mutation detailsA spontaneous deletion removed 138 kb, including exons 1-5 of Elmod1 and Tnfaip8l3. Western blot analysis confirmed the absence of protein expression in the brain. (J:187273)
Inheritance:    Recessive
Molecular structure of the rda mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any rda Mutation:  1 strain or line available
References
Original:  J:187273 Johnson KR, et al., Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia. PLoS One. 2012;7(4):e36074
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/16/2021
MGI 6.17
The Jackson Laboratory