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Pla2g6tm1Turk
Targeted Allele Detail
Nomenclature
Symbol: Pla2g6tm1Turk
Name: phospholipase A2, group VI; targeted mutation 1, John Turk
MGI ID: MGI:3055154
Synonyms: IPLA2beta-
Gene: Pla2g6  Location: Chr15:79286228-79328390 bp, - strand  Genetic Position: Chr15, 37.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92835
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pla2g6 Mutation:  23 strains or lines available
Notes
This model of infantile neuroaxonal dystrophy has a later onset in mouse than in human

References
Original:  J:92835 Bao S, et al., Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility. J Biol Chem. 2004 Sep 10;279(37):38194-200
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory