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Tg(MGMT)3Bec
Transgene Detail
Nomenclature
Symbol: Tg(MGMT)3Bec
Name: transgene insertion 3, Klaus Becker
MGI ID: MGI:3055098
Transgene: Tg(MGMT)3Bec  Location: unknown  
Transgene
origin
Strain of Origin:  NMRI
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MGMT)3Bec expresses 1 gene
 
Mutation detailsTransgene contains a cytokeratin (Ck) promoter that directs skin targeted overexpression of the human DNA repair protein MGMT (O6-methylguanine-DNA methyltransferase). (J:92925)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:92925 Becker K, et al., Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. Cancer Res. 1996 Jul 15;56(14):3244-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory