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Rasd1tm1Pngr
Targeted Allele Detail
Nomenclature
Symbol: Rasd1tm1Pngr
Name: RAS, dexamethasone-induced 1; targeted mutation 1, Josef M Penninger
MGI ID: MGI:3054834
Synonyms: dexras1-
Gene: Rasd1  Location: Chr11:59963181-59964944 bp, - strand  Genetic Position: Chr11, 37.81 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92624
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsNucleotides encoding amino acids 13-227 were replaced with a neomycin resistance gene. The deleted sequence encompassed the GTP binding and hydrolysis domain and the effector loop. Transcripts were undetectable in RT-PCR or Northern blot of mutant brain tissue. (J:92624)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasd1 Mutation:  11 strains or lines available
References
Original:  J:92624 Cheng HY, et al., Dexras1 potentiates photic and suppresses nonphotic responses of the circadian clock. Neuron. 2004 Sep 2;43(5):715-28
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory