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Tg(SREBP1a)7343Reh
Transgene Detail
Nomenclature
Symbol: Tg(SREBP1a)7343Reh
Name: transgene insertion 7343, Robert E Hammer
MGI ID: MGI:3054654
Synonyms: S+, Tg(SREBF1)2Mbjg, TgSREBP-1a
Transgene: Tg(SREBP1a)7343Reh  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(SREBP1a)7343Reh expresses 1 gene
 
Mutation detailsThe transgene contains human sterol regulatory element binding transcription factor 1 (SREBF1) under control of the phosphoenolpyruvate carboxykinase (Pck1) promoter. Seven lines were created. (J:35770)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:35770 Shimano H, et al., Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a [see comments]. J Clin Invest. 1996 Oct 1;98(7):1575-84
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory