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Catb
Radiation induced Allele Detail
Nomenclature
Symbol: Catb
Name: catalase; acatalasemia
MGI ID: MGI:3053604
Synonyms: Csb, M1
Gene: Cat  Location: Chr2:103453849-103485160 bp, - strand  Genetic Position: Chr2, 54.43 cM
Mutation
origin
Strain of Origin:  (101 x C3H)F1
Mutation
description
Allele Type:    Radiation induced
Mutation:    Nucleotide substitutions
 
Mutation detailsThis allele corresponds to a mutation located in the first alpha helix in the amino terminal arm of the catalase subunit. The substitution of G to T results in an amino acid substitution that replaces glutamine with histidine at position 11. (J:10926)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cat Mutation:  12 strains or lines available
References
Original:  J:5015 Feinstein RN, et al., Acatalasemic and hypocatalasemic mouse mutants. Genetics. 1966 May;53(5):923-33
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory