Tg(TNNT2-deltaGlu160)15Imeg
Transgene Detail

Summary

• Symbol: Tg(TNNT2-deltaGlu160)15Imeg
• Name: transgene insertion 15, Institute of Molecular Embryology and Genetics
• MGI ID: MGI:3053202
• Synonyms: TgN(cTnT delta Glu160)15Imeg
• Transgene: Tg(TNNT2-deltaGlu160)15Imeg Location: unknown
• Alliance: Tg(TNNT2-deltaGlu160)15Imeg page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TNNT2-deltaGlu160)15Imeg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNNT2 (7139)

  Tnnt2

  (MGI:104597)

• Mutation details: The transgene encodes a mutant human troponin T2, cardiac having a single-codon, in-frame deletion of the glutamic acid at amino acid position 160. This mutation was identified in affected members of families having dominantly inherited left ventricular hypertrophic cardiomyopathy which, although often mild or subclinical, is associated with a high incidence of sudden death at an early age. (J:91746)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:91655 Center for Animal Resources and Development, Information obtained from the Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan. Unpublished. 2004-2103
• All: 2 reference(s)