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Scn9atm1.1Jnw
Targeted Allele Detail
Nomenclature
Symbol: Scn9atm1.1Jnw
Name: sodium channel, voltage-gated, type IX, alpha; targeted mutation 1.1, John N Wood
MGI ID: MGI:3053098
Synonyms: Nav1.7-
Gene: Scn9a  Location: Chr2:66480080-66634962 bp, - strand  Genetic Position: Chr2, 39.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92442
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCrossing Scn9atm1Jnw with mice ubiquitously expressing Cre removes exons 14 and 15. Southern blot confirmed recombination in mutants. (J:92442)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scn9a Mutation:  66 strains or lines available
References
Original:  J:92442 Nassar MA, et al., Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12706-11
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory