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Tnfrsf13btm1Cmac
Targeted Allele Detail
Nomenclature
Symbol: Tnfrsf13btm1Cmac
Name: tumor necrosis factor receptor superfamily, member 13b; targeted mutation 1, Charles R Mackay
MGI ID: MGI:3052983
Synonyms: TACI-
Gene: Tnfrsf13b  Location: Chr11:61126755-61149372 bp, + strand  Genetic Position: Chr11, 37.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91914
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA tailless human CD2 reporter cDNA and PGK-neo replaced 6.12 kb immediately downstream of the ATG, including nucleotides encoding amino acids 1-89. As a result, stop codons were introduced in each possible reading frame downstream of the inserted reporter. (J:91914)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf13b Mutation:  1 strain or line available
References
Original:  J:91914 Ng LG, et al., B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol. 2004 Jul 15;173(2):807-17
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory