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Ptger4tm1.1Matb
Targeted Allele Detail
Nomenclature
Symbol: Ptger4tm1.1Matb
Name: prostaglandin E receptor 4 (subtype EP4); targeted mutation 1.1, Matthew D Breyer
MGI ID: MGI:3052967
Synonyms: EP4flox
Gene: Ptger4  Location: Chr15:5206661-5244187 bp, - strand  Genetic Position: Chr15, 1.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92301
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe neo cassette was removed via partial cre recombination leaving loxP sites surrounding exon 2, which encodes slightly more than five of the seven transmembrane-spanning domains. Recombination in mutant mice was confirmed by Southern blot and PCR. (J:92031)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptger4 Mutation:  16 strains or lines available
References
Original:  J:92301 Schneider A, et al., Generation of a conditional allele of the mouse prostaglandin EP(4) receptor. Genesis. 2004 Sep;40(1):7-14
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/17/2018
MGI 6.12
The Jackson Laboratory