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Gp2tm1Soka
Targeted Allele Detail
Nomenclature
Symbol: Gp2tm1Soka
Name: glycoprotein 2 (zymogen granule membrane); targeted mutation 1, S Fukuoka
MGI ID: MGI:3052837
Synonyms: Gp2-
Gene: Gp2  Location: Chr7:119041760-119058495 bp, - strand  Genetic Position: Chr7, 63.88 cM, cytoband F1-F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92161
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA targeting vector was designed to replace part of exon 3 and exon 4 with a PGK-beta-geo selection cassette. Southern blotting identified correctly targeted cells. RT-PCR showed that expression was completely abolished. (J:92161)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gp2 Mutation:  29 strains or lines available
References
Original:  J:92161 Kobayashi K, et al., GP2/THP gene family of self-binding, GPI-anchored proteins forms a cluster at chromosome 7F1 region in mouse genome. Biochem Biophys Res Commun. 2004 Sep 17;322(2):659-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory