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Pex7tm1Rjaw
Targeted Allele Detail
Nomenclature
Symbol: Pex7tm1Rjaw
Name: peroxisomal biogenesis factor 7; targeted mutation 1, Ronald JA Wanders
MGI ID: MGI:3052739
Synonyms: Pex7-
Gene: Pex7  Location: Chr10:19860090-19907674 bp, - strand  Genetic Position: Chr10, 9.16 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92346
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA beta galactosidase reporter gene fused with a neomycin phosphotransferas gene (beta geo cassette) replaced exon 3 and parts of introns 2 and 3 of the gene. (J:92346)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pex7 Mutation:  9 strains or lines available
References
Original:  J:92346 Brites P, et al., Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata. Hum Mol Genet. 2003 Sep 15;12(18):2255-67
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory