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Tinf2tm1Yjc
Targeted Allele Detail
Nomenclature
Symbol: Tinf2tm1Yjc
Name: Terf1 (TRF1)-interacting nuclear factor 2; targeted mutation 1, Y Jeffrey Chiang
MGI ID: MGI:3052712
Synonyms: Tin2-
Gene: Tinf2  Location: Chr14:55679083-55681817 bp, - strand  Genetic Position: Chr14, 28.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92239
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene was inserted into exon 1 upstream of the ATG. Southern blot and PCR confirmed recombination in mice. (J:92239)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tinf2 Mutation:  6 strains or lines available
References
Original:  J:92239 Chiang YJ, et al., Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway. Mol Cell Biol. 2004 Aug;24(15):6631-4
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory