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Tg(Pax6-cre,GFP)2Pgr
Transgene Detail
Nomenclature
Symbol: Tg(Pax6-cre,GFP)2Pgr
Name: transgene insertion 2, Peter Gruss
MGI ID: MGI:3052661
Synonyms: alpha-cre, alphaP0CREiresGFP, aPax6-Cre, Pax6-aCre, Pax6-alpha-Cre, Tg(Pax6-cre,-GFP)2Pgr
Transgene: Tg(Pax6-cre,GFP)2Pgr  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThis transgene consists of a minimal promoter, 1.8 kb of murine Pax6 intron 4 encoding a retinal specific regulatory element, a cre recombinase gene, an IRES, a GFP gene, and a polyadenylation signal. Cre and GFP expression are seen in retinal progenitor cells. (J:68851)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pax6     Summary of all recombinase alleles driven by Pax6. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:68851 Marquardt T, et al., Pax6 is required for the multipotent state of retinal progenitor cells. Cell. 2001 Apr 6;105(1):43-55
All:  104 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory