Tg(Neurog3-cre)C1Able
Transgene Detail
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Symbol: |
Tg(Neurog3-cre)C1Able |
Name: |
transgene insertion C1, Andrew B Leiter |
MGI ID: |
MGI:3052639 |
Synonyms: |
Neurgo3TgBAC-Cre, Neurog3(cre), Neurog3Cre, ngn3-Cre, Tg(Neurog3-cre)#Able |
Transgene: |
Tg(Neurog3-cre)C1Able Location: unknown
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Alliance: |
Tg(Neurog3-cre)C1Able page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Neurog3-cre)C1Able expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Neurog3 (MGI:893591) |
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Mutation details: The Cre recombinase coding sequence, flanked by a nuclear localization signal and an SV40 polyadenylation site, was inserted just after the translation start site of the neurogenin 3 gene present in mouse BAC RP23-121F10, which also includes approximately 81 kb of 5' and 102 kb of 3' flanking DNA. Immunohistochemical analysis shows the same expression pattern for cre as for neurogenin 3 in adult and embryonic mice bearing this transgene. Cre recombinase activity is seen in cell types of pancreas, stomach, small intestine and colon that express or are descended from cells that express neurogenin 3 during development.
(J:92204)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Neurog3
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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This is one of two independent lines demonstrating identical expression patterns.
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Original: |
J:92204 Schonhoff SE, et al., Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types. Dev Biol. 2004 Jun 15;270(2):443-54 |
All: |
90 reference(s) |
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