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Timelesstm1Rep
Targeted Allele Detail
Nomenclature
Symbol: Timelesstm1Rep
Name: timeless circadian clock 1; targeted mutation 1, Steven M Reppert
MGI ID: MGI:3051143
Gene: Timeless  Location: Chr10:128232065-128252941 bp, + strand  Genetic Position: Chr10, 76.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63669
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced coding sequence after codon 178. A reduced amount of encoded protein was detected in heterozygous animals. (J:63669)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Timeless Mutation:  35 strains or lines available
References
Original:  J:63669 Gotter AL, et al., A time-less function for mouse timeless. Nat Neurosci. 2000 Aug;3(8):755-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory