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Nr5a2tm1Bel
Targeted Allele Detail
Summary
Symbol: Nr5a2tm1Bel
Name: nuclear receptor subfamily 5, group A, member 2; targeted mutation 1, Luc Belanger
MGI ID: MGI:3050234
Synonyms: FTF-, FTF-lacZ, NR5A2-
Gene: Nr5a2  Location: Chr1:136770309-136888186 bp, - strand  Genetic Position: Chr1, 59.98 cM, cytoband E4
Alliance: Nr5a2tm1Bel page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91695
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ gene was inserted in phase in exon 4. An MC1-neo cassette was also inserted in exon 4 immediately following the LacZ insert but in reverse orientation. (J:91695)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr5a2 Mutation:  94 strains or lines available
References
Original:  J:91695 Pare JF, et al., The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element. J Biol Chem. 2004 May 14;279(20):21206-16
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory