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Dnmt3atm3.2Enl
Targeted Allele Detail
Nomenclature
Symbol: Dnmt3atm3.2Enl
Name: DNA methyltransferase 3A; targeted mutation 3.2, En Li
MGI ID: MGI:3047824
Synonyms: Dnmt3a1lox
Gene: Dnmt3a  Location: Chr12:3806007-3914443 bp, + strand  Genetic Position: Chr12, 1.99 cM, cytoband A2-A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91108
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was created by crossing Dnmt3atm3.1Enl with TNAP-cre mice, thereby excising the floxed exon 19. (J:91108)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 19 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnmt3a Mutation:  106 strains or lines available
References
Original:  J:91108 Kaneda M, et al., Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature. 2004 Jun 24;429(6994):900-3
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory