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Pax7tm2Pgr
Targeted Allele Detail
Nomenclature
Symbol: Pax7tm2Pgr
Name: paired box 7; targeted mutation 2, Peter Gruss
MGI ID: MGI:3047633
Synonyms: Pax7lacZ
Gene: Pax7  Location: Chr4:139737062-139833528 bp, - strand  Genetic Position: Chr4, 70.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:32018
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA beta-galactosidase and neo cassette was inserted in frame into the first exon of the paired box. Whole-mount staining for beta-gal indicated gene expression in the rhombencephalon of mutant embryos. (J:32018)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pax7 Mutation:  33 strains or lines available
Notes
ES cell line = D3 (129S2/SvPas) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).
References
Original:  J:32018 Mansouri A, et al., Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice. Development. 1996 Mar;122(3):831-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory