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Targeted Allele Detail
Symbol: Bach2tm1Igar
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 1, Kazuhiko Igarashi
MGI ID: MGI:3047541
Synonyms: Bach2-
Gene: Bach2  Location: Chr4:32238804-32586104 bp, + strand  Genetic Position: Chr4, 14.02 cM, cytoband A4
Germline Transmission:  Earliest citation of germline transmission: J:91110
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first coding exon was replaced with a floxed neo and lacZ gene cassette. Southern blot confirmed recombination and Western blot of bone marrow B cell did not detect protein in mutants. (J:91110)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bach2 Mutation:  21 strains or lines available
Original:  J:91110 Muto A, et al., The transcriptional programme of antibody class switching involves the repressor Bach2. Nature. 2004 Jun 3;429(6991):566-71
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory