About   Help   FAQ
Bach2tm1Igar
Targeted Allele Detail
Nomenclature
Symbol: Bach2tm1Igar
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 1, Kazuhiko Igarashi
MGI ID: MGI:3047541
Synonyms: Bach2-
Gene: Bach2  Location: Chr4:32238804-32586104 bp, + strand  Genetic Position: Chr4, 14.02 cM, cytoband A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91110
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first coding exon was replaced with a floxed neo and lacZ gene cassette. Southern blot confirmed recombination and Western blot of bone marrow B cell did not detect protein in mutants. (J:91110)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bach2 Mutation:  17 strains or lines available
References
Original:  J:91110 Muto A, et al., The transcriptional programme of antibody class switching involves the repressor Bach2. Nature. 2004 Jun 3;429(6991):566-71
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/29/2016
MGI 6.06
The Jackson Laboratory