Tg(Wnt1-GAL4)1Rth
Transgene Detail

Summary

• Symbol: Tg(Wnt1-GAL4)1Rth
• Name: transgene insertion 1, David H Rowitch
• MGI ID: MGI:3047162
• Synonyms: WEXP2-GAL4, WEXP-GAL4, Wnt-1/GAL4
• Transgene: Tg(Wnt1-GAL4)1Rth Location: unknown
• Alliance: Tg(Wnt1-GAL4)1Rth page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of murine Wnt1 regulatory sequences driving expression of a yeast GAL4 DNA fragment. Crossing with a UAS-lacZ transgenic mouse confirmed that the expression pattern matched that of endogenous Wnt1. Six lines were generated and one with a high level of activity selected for further study. (J:57948)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:57948 Rowitch DH, et al., Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci. 1999 Oct 15;19(20):8954-65
• All: 4 reference(s)