Fxr1^tm1.1Dln
Targeted Allele Detail

Summary

• Symbol: Fxr1^tm1.1Dln
• Name: FMR1 autosomal homolog 1; targeted mutation 1.1, David L Nelson
• MGI ID: MGI:3046847
• Gene: Fxr1 Location: Chr3:34074133-34124129 bp, + strand Genetic Position: Chr3, 16.41 cM, cytoband B
• Alliance: Fxr1^tm1.1Dln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91191
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Transient Cre expression in Fxr1h^tm1Dln excised the floxed neo, leaving loxp sites before and after the promoter and exon 1. (J:91191)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fxr1 Mutation: 164 strains or lines available

References

• Original: J:91191 Mientjes EJ, et al., Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet. 2004 Jul 1;13(13):1291-302
• All: 8 reference(s)