Tg(TcrbB3)8Cbn
Transgene Detail

Summary

• Symbol: Tg(TcrbB3)8Cbn
• Name: transgene insertion 8, Frank Carbone
• MGI ID: MGI:3046668
• Synonyms: Vbeta5 Tg, Vbeta5⁺ transgenic
• Transgene: Tg(TcrbB3)8Cbn Location: unknown
• Alliance: Tg(TcrbB3)8Cbn page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TcrbB3)8Cbn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcrb (MGI:98578)

• Mutation details: More than 10 copies of a BAC clone containing a Tcr beta chain originally derived from an OVA-specific cytotoxic T lymphocyte line B3 were inserted. The transgenic beta-chain gene consists of vbeta5.2/Dbeta2/Jbeta2.6, cbeta2 and the endogenous promoter and enhancer. (J:91386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:91386 Carbone FR, et al., T cell receptor alpha-chain pairing determines the specificity of residue 262 within the Kb-restricted, ovalbumin257-264 determinant. Int Immunol. 1992 Aug;4(8):861-7
• All: 25 reference(s)