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Olfr151tm6Mom
Targeted Allele Detail
Nomenclature
Symbol: Olfr151tm6Mom
Name: olfactory receptor 151; targeted mutation 6, Peter Mombaerts
MGI ID: MGI:3045144
Synonyms: Hyb F, M71-M72 hybrid F
Gene: Olfr151  Location: Chr9:37729977-37731061 bp, - strand  Genetic Position: Chr9, 20.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90716
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Olfr151tm6Mom expresses 1 gene
 
Mutation detailsSix bp changes resulting in 4 amino acid substitutions (T2A, G15R, A146V, V151M) and an IRES-tauGFP gene were introduced via homologous recombination. The resulting protein is a hybrid between Olfr151 and Olfr160 which have a total of 25 bp and 11 amino acid differences. The GFP gene was fused after the stop codon and co-expressed with the mutant protein. (J:90716)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Olfr151 Mutation:  60 strains or lines available
References
Original:  J:90716 Feinstein P, et al., A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell. 2004 Jun 11;117(6):817-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/12/2020
MGI 6.15
The Jackson Laboratory