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Foxl2tm1Gpil
Targeted Allele Detail
Nomenclature
Symbol: Foxl2tm1Gpil
Name: forkhead box L2; targeted mutation 1, Giuseppe Pilia
MGI ID: MGI:3044226
Synonyms: Foxl2-
Gene: Foxl2  Location: Chr9:98955607-98956847 bp, + strand  Genetic Position: Chr9, 51.41 cM, cytoband E4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90371
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region, contained within one exon, was replaced with a neo cassette. Southern blot confirmed recombination in mutant ES cells. (J:90371)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 9 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxl2 Mutation:  2 strains or lines available
References
Original:  J:90371 Uda M, et al., Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development. Hum Mol Genet. 2004 Jun 1;13(11):1171-81
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory