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Wfs1tm1Yoka
Targeted Allele Detail
Nomenclature
Symbol: Wfs1tm1Yoka
Name: Wolfram syndrome 1 homolog (human); targeted mutation 1, Yoshitomo Oka
MGI ID: MGI:3044175
Synonyms: wfs1-
Gene: Wfs1  Location: Chr5:36966104-36988982 bp, - strand  Genetic Position: Chr5, 19.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90420
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (knock-out)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wfs1 Mutation:  6 strains or lines available
References
Original:  J:90420 Ishihara H, et al., Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet. 2004 Jun 1;13(11):1159-70
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory