Tg(Mbp-PDGFB)90Ubc
Transgene Detail

Summary

• Symbol: Tg(Mbp-PDGFB)90Ubc
• Name: transgene insertion 90, Uppsala University
• MGI ID: MGI:3044166
• Synonyms: KFN-1, MBP-PDGF B, MBP-PDGF-B
• Transgene: Tg(Mbp-PDGFB)90Ubc Location: unknown
• Alliance: Tg(Mbp-PDGFB)90Ubc page

Transgene origin

• Strain of Origin: (C57BL/6NCrl x C3H/HeNCrl)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mbp-PDGFB)90Ubc expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PDGFB (5155)

  Pdgfb

  (MGI:97528)

• Mutation details: The transgene comprises 3.2 kb of the 5' flanking sequence of the mouse myelin basic protein gene ligated to the human PDGFB minimal coding sequence, lacking the 5' and 3' untranslated sequences, followed by the SV40 late polyadenylation signal. (J:90555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:90555 Forsberg-Nilsson K, et al., Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts. Glia. 2003 Feb;41(3):276-89
• All: 1 reference(s)