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Ppp3r1tm2.1Grc
Targeted Allele Detail
Nomenclature
Symbol: Ppp3r1tm2.1Grc
Name: protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); targeted mutation 2.1, Gerald R Crabtree
MGI ID: MGI:3044031
Synonyms: Cnb1delta
Gene: Ppp3r1  Location: Chr11:17159298-17200380 bp, + strand  Genetic Position: Chr11, 9.71 cM, cytoband A3.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89771
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination of the single loxP sites in Ppp3r1tm2Grc resulted in the deletion of exons 3 through 5. (J:89771)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp3r1 Mutation:  27 strains or lines available
References
Original:  J:89771 Neilson JR, et al., Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity. 2004 Mar;20(3):255-66
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory