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Il1rl1tm1Brl
Targeted Allele Detail
Nomenclature
Symbol: Il1rl1tm1Brl
Name: interleukin 1 receptor-like 1; targeted mutation 1, RCC, Ltd
MGI ID: MGI:3043989
Synonyms: TgH(GS-T1)Brl
Gene: Il1rl1  Location: Chr1:40429570-40465415 bp, + strand  Genetic Position: Chr1, 19.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63507
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details4.8 kb of the endogenous gene, including part of exon 2 and all of exons 3 to 6, were deleted and replaced by the lacZ gene followed by a neomycin resistance gene. Expression of the endogenous gene was abolished. Expression of beta-galactosidase was not reported. (J:63507)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Il1rl1 Mutation:  18 strains or lines available
References
Original:  J:63507 Senn KA, et al., T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis. Eur J Immunol. 2000 Jul;30(7):1929-38
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory