Nr4a3tm1Wnt
Targeted Allele Detail
|
Symbol: |
Nr4a3tm1Wnt |
Name: |
nuclear receptor subfamily 4, group A, member 3; targeted mutation 1, Astar Winoto |
MGI ID: |
MGI:3043761 |
Synonyms: |
Nor-1 - |
Gene: |
Nr4a3 Location: Chr4:48045153-48086447 bp, + strand Genetic Position: Chr4, 26.07 cM, cytoband B2
|
Alliance: |
Nr4a3tm1Wnt page
|
|
Abnormal mesoderm accumulation in E7 Nr4a3tm1Wnt/Nr4a3tm1Wnt embryos
Show the 1 phenotype image(s) involving this allele.
|
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:89944
|
Parent Cell Line: |
J1 (ES Cell)
|
Strain of Origin: |
129S4/SvJae
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: A portion of exon 3 containing the transcriptional activation domain and part of the DNA binding domain was replaced with a neo cassette via homologous recombination. In situ hybridization confirmed the absence of RNA expression in homozygous embryos.
(J:89944)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Nr4a3 Mutation: |
53 strains or lines available
|
|
Original: |
J:89944 DeYoung RA, et al., The orphan steroid receptor Nur77 family member Nor-1 is essential for early mouse embryogenesis. J Biol Chem. 2003 Nov 21;278(47):47104-9 |
All: |
2 reference(s) |
|