Htt^tm3Detl
Targeted Allele Detail

Nomenclature

Symbol:	Htt^tm3Detl
Name:	huntingtin; targeted mutation 3, Peter J Detloff
MGI ID:	MGI:3043022
Gene:	Htt  Location: Chr5:34761740-34912534 bp, + strand  Genetic Position: Chr5, 17.92 cM

Mutation origin

Germline Transmission:	Earliest citation of germline transmission: J:67074
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt^b-m3

Mutation description

Allele Type:		Targeted (knock-out)
Mutations:		Insertion, Intragenic deletion
		Exon 1 and the promoter were replaced with an HPRT minigene. (J:67074)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htt Mutation:	40 strains or lines available

References

Original:	J:67074 Lin CH, et al., Neurological abnormalities in a knock-in mouse model of Huntington's disease. Hum Mol Genet. 2001 Jan 15;10(2):137-44
All:	2 reference(s)