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Kcna3tm1Gvd
Targeted Allele Detail
Nomenclature
Symbol: Kcna3tm1Gvd
Name: potassium voltage-gated channel, shaker-related subfamily, member 3; targeted mutation 1, Gary V Desir
MGI ID: MGI:3042596
Synonyms: Kv1.3-
Gene: Kcna3  Location: Chr3:107036169-107038070 bp, + strand  Genetic Position: Chr3, 46.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89447
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced the promoter region and the 5' third of the coding region. Western blot detected no wild-type protein in mutants. (J:89447)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcna3 Mutation:  7 strains or lines available
References
Original:  J:89447 Xu J, et al., The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight. Hum Mol Genet. 2003 Mar 1;12(5):551-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/19/2017
MGI 6.10
The Jackson Laboratory