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Targeted Allele Detail
Symbol: Nbl1tm1Saki
Name: neuroblastoma, suppression of tumorigenicity 1; targeted mutation 1, S Sakiyama
MGI ID: MGI:3042574
Synonyms: Dan-
Gene: Nbl1  Location: Chr4:139082284-139092993 bp, - strand  Genetic Position: Chr4, 70.57 cM, cytoband D3
Germline Transmission:  Earliest citation of germline transmission: J:89353
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 2.5 kb fragment including exons 2 and 3 was replaced with an MC1-Neo cassette. RT-PCR confirmed the absence of RNA expression in homozygotes. (J:89353)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nbl1 Mutation:  10 strains or lines available
Original:  J:89353 Ohtori S, et al., Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma. Mol Cell Neurosci. 2004 Mar;25(3):504-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory