Mobp^tm1Sak
Targeted Allele Detail

Summary

• Symbol: Mobp^tm1Sak
• Name: myelin-associated oligodendrocytic basic protein; targeted mutation 1, Saburo Sakoda
• MGI ID: MGI:3042483
• Gene: Mobp Location: Chr9:119978773-120010550 bp, + strand Genetic Position: Chr9, 71.41 cM
• Alliance: Mobp^tm1Sak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89416
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first coding exon was replaced with a neo cassette. No protein was detected from mutant mice in western blot analysis. (J:89416)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mobp Mutation: 29 strains or lines available

References

• Original: J:89416 Yamamoto Y, et al., Myelin-associated oligodendrocytic basic protein is essential for normal arrangement of the radial component in central nervous system myelin. Eur J Neurosci. 1999 Mar;11(3):847-55
• All: 2 reference(s)