Tg(Mt1-rPRL)2Jto
Transgene Detail

Summary

• Symbol: Tg(Mt1-rPRL)2Jto
• Name: transgene insertion 2, Jan Tornell
• MGI ID: MGI:3040916
• Synonyms: Mt-1-rPRL
• Transgene: Tg(Mt1-rPRL)2Jto Location: unknown
• Alliance: Tg(Mt1-rPRL)2Jto page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-rPRL)2Jto expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Prl (24683)

  Prl	(MGI:97762)

• Mutation details: This transgene contains the mouse metallothionein promoter and the wild-type allele of the rat prolactin gene. Prolactin expression was at a more moderate level (11ng/ml). (J:43355)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Mt1-rPRL)2Jto

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Line 1 was also produced.

References

• Original: J:43355 Wennbo H, et al., Transgenic mice overexpressing the prolactin gene develop dramatic enlargement of the prostate gland. Endocrinology. 1997 Oct;138(10):4410-5
• All: 1 reference(s)