Tg(NF2dCt)1Gth
Transgene Detail

Summary

• Symbol: Tg(NF2dCt)1Gth
• Name: transgene insertion 1, Gilles Thomas
• MGI ID: MGI:3039715
• Synonyms: P0-Sch-deltaCter, Tg(NF2dCt)#Gth
• Transgene: Tg(NF2dCt)1Gth Location: unknown
• Alliance: Tg(NF2dCt)1Gth page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(NF2dCt)1Gth expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NF2 (4771)

  Nf2	(MGI:97307)

• Mutation details: The transgene contains the rat myelin protein zero promoter and a cDNA encoding the human neurofibromatosis type 2 protein (Schwannomin) truncated at amino acid 314, and tagged with the 11 C-terminal amino acids of the VSV-G protein. (J:54466)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Line 3 was also produced.

References

• Original: J:54466 Giovannini M, et al., Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein. Genes Dev. 1999 Apr 15;13(8):978-86
• All: 2 reference(s)