Tg(MMTV-MAT)3Lmm
Transgene Detail

Summary

• Symbol: Tg(MMTV-MAT)3Lmm
• Name: transgene insertion 3, Lynn M Matrisian
• MGI ID: MGI:3039686
• Transgene: Tg(MMTV-MAT)3Lmm Location: unknown
• Alliance: Tg(MMTV-MAT)3Lmm page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The wild-type human MMP7 (matrix metalloproteinase 7, MAT) gene was placed under the control of the mouse mammary tumor virus promoter. (J:71574)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-MAT)3Lmm

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:71574 Rudolph-Owen LA, et al., Overexpression of the matrix metalloproteinase matrilysin results in premature mammary gland differentiation and male infertility. Mol Biol Cell. 1998 Feb;9(2):421-35
• All: 3 reference(s)