Tg(MMTV-Fgf7)1Led
Transgene Detail

Summary

• Symbol: Tg(MMTV-Fgf7)1Led
• Name: transgene insertion 1, Philip Leder
• MGI ID: MGI:3039534
• Synonyms: MMTV-kgf
• Transgene: Tg(MMTV-Fgf7)1Led Location: unknown
• Alliance: Tg(MMTV-Fgf7)1Led page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Fgf7)1Led expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgf7 (MGI:95521)

• Mutation details: This transgene contains the mouse mammary tumor virus promoter and the mouse fibroblast growth factor gene [also called "Kgf" or keratinocyte growth factor]. It also contains SV40 poly A. (J:37679)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-Fgf7)1Led

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Two founder lines were produced but no distinction was made between them. FVB/N females carrying this transgene cannot nurse their young.

References

• Original: J:37679 Kitsberg DI, et al., Keratinocyte growth factor induces mammary and prostatic hyperplasia and mammary adenocarcinoma in transgenic mice. Oncogene. 1996 Dec 19;13(12):2507-15
• All: 3 reference(s)