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Llgl1tm1Vv
Targeted Allele Detail
Nomenclature
Symbol: Llgl1tm1Vv
Name: LLGL1 scribble cell polarity complex component; targeted mutation 1, Valeri Vasioukhin
MGI ID: MGI:3039268
Gene: Llgl1  Location: Chr11:60590549-60605012 bp, + strand  Genetic Position: Chr11, 37.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89028
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe exon immediately downstream of the first coding exon was left flanked by single loxP sites following cre-mediated excision of an IRES-betageo cassette used for selection. (J:89028)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Llgl1 Mutation:  45 strains or lines available
References
Original:  J:89028 Klezovitch O, et al., Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev. 2004 Mar 1;18(5):559-71
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory