Tg(betah1-T)13Cps
Transgene Detail

Summary

• Symbol: Tg(betah1-T)13Cps
• Name: transgene insertion 13, Carlos Perez-Stable
• MGI ID: MGI:3039069
• Synonyms: beta h1/T
• Transgene: Tg(betah1-T)13Cps Location: unknown
• Alliance: Tg(betah1-T)13Cps page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the mouse hemoglobin Z, beta-like embryonic chain promoter (Hbb-bh1) and the wild-type allele of the SV40 large T antigen (TAg) gene. (J:79828)

Tumor Data

List all tumor models in MMHCdb carrying Tg(betah1-T)13Cps

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

On a genetic background that involves C57BL/6 and CBA, this line shows 50% frequency of choroid plexus tumors. Three additional lines (#s 3, 5, and 37) on the same genetic background range in tumor frequency from 0% for line 3 to 20% for line 5.

References

• Original: J:79828 Perez-Stable C, Distinct negative regulatory mechanisms involved in the repression of human embryonic epsilon- and fetal G gamma-globin genes in transgenic mice. J Biol Chem. 1994 Dec 30;269(52):33109-15
• All: 2 reference(s)