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Tg(C3-1-TAg)cJeg
Transgene Detail
Summary
Symbol: Tg(C3-1-TAg)cJeg
Name: transgene insertion c, Jeffrey E Green
MGI ID: MGI:3039067
Synonyms: C3(1)/SV40, C3(1)/SV40T, C3(1)-SV40 T antigen, C3(1)-Tag, C3(1)/Tag, C3(1)/TAg, C3(1)/T(AG), C3(1)/T antigen (Tag), C3Tag, C3-TAg, Large T, Tg(Scgb2a2-TAg)cJeg
Transgene: Tg(C3-1-TAg)cJeg  Location: unknown  
Alliance: Tg(C3-1-TAg)cJeg page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene contains the rat prostatic binding protein C3 promoter (Pbpc3) and the wild-type allele of the SV40 large tumor antigen (TAg) gene. Founder c carried 6 copies of the transgene. Founders f, g, i, j, k, and l were also generated. Two transgenic lines (c and l) were produced. (J:52786)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(C3-1-TAg)cJeg
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:52786 Maroulakou IG, et al., Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11236-40
All:  89 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory