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Nr4a3tm1Omc
Targeted Allele Detail
Nomenclature
Symbol: Nr4a3tm1Omc
Name: nuclear receptor subfamily 4, group A, member 3; targeted mutation 1, Orla M Conneely
MGI ID: MGI:3037444
Synonyms: nor-1-
Gene: Nr4a3  Location: Chr4:48045153-48086447 bp, + strand  Genetic Position: Chr4, 26.07 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73971
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ gene and neomycin selection cassette were inserted into exon 2. Beta-galactosidase was expressed from this allele in a pattern similar to the endogenous gene. (J:73971)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr4a3 Mutation:  22 strains or lines available
References
Original:  J:73971 Ponnio T, et al., The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb;22(3):935-45
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2022
MGI 6.21
The Jackson Laboratory