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Tg(PML-RARA)556Kog
Transgene Detail
Nomenclature
Symbol: Tg(PML-RARA)556Kog
Name: transgene insertion 556, Scott Kogan
MGI ID: MGI:3033300
Synonyms: hMRP8-PML-RARalpha, MRP8-PMLRARalpha, PML/RARalpha
Transgene: Tg(PML-RARA)556Kog  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Line #556 has the highest level of transgene expression of the nine lines created for this study. All mice carrying this transgene on an FVB/N genetic background developed skin papillomas.

References
Original:  J:39327 Brown D, et al., A PMLRARalpha transgene initiates murine acute promyelocytic leukemia. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2551-6
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory