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Targeted Allele Detail
Symbol: Syn1tm1Noh
Name: synapsin I; targeted mutation 1, Nobutaka Hirokawa
MGI ID: MGI:3032534
Synonyms: X-13
Gene: Syn1  Location: ChrX:20860511-20921004 bp, - strand  Genetic Position: ChrX, 16.37 cM, cytoband A1-A4
Germline Transmission:  Earliest citation of germline transmission: J:30400
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced part of exon 1 and intron 1. Western blot analysis confirmed the absence of encoded protein in brain extracts derived from homozygous mice. (J:30400)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syn1 Mutation:  19 strains or lines available
Original:  J:30400 Takei Y, et al., Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system. J Cell Biol. 1995 Dec;131(6 Pt 2):1789-800
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory