About   Help   FAQ
Avpr1btm1Gzt
Targeted Allele Detail
Nomenclature
Symbol: Avpr1btm1Gzt
Name: arginine vasopressin receptor 1B; targeted mutation 1, Gozoh Tsujimoto
MGI ID: MGI:3029988
Synonyms: V1bR-, V1bR KO
Gene: Avpr1b  Location: Chr1:131599239-131612000 bp, + strand  Genetic Position: Chr1, 57.09 cM, cytoband E4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87707
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.5-kb region including the first exon and part of the first intron of the gene was replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by RT-PCR analysis of homozygous mutant mice. (J:87707)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Avpr1b Mutation:  23 strains or lines available
References
Original:  J:87707 Tanoue A, et al., The vasopressin V1b receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions. J Clin Invest. 2004 Jan;113(2):302-9
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory