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Ntsr1tm1Hmno
Targeted Allele Detail
Nomenclature
Symbol: Ntsr1tm1Hmno
Name: neurotensin receptor 1; targeted mutation 1, Hiroshi Maeno
MGI ID: MGI:3029204
Gene: Ntsr1  Location: Chr2:180499976-180544980 bp, + strand  Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87872
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2, which encodes the fifth and sixth transmembrane domains, was replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by RT-PCR analysis. (J:87872)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntsr1 Mutation:  17 strains or lines available
References
Original:  J:87872 Maeno H, et al., Comparison of mice deficient in the high- or low-affinity neurotensin receptors, Ntsr1 or Ntsr2, reveals a novel function for Ntsr2 in thermal nociception. Brain Res. 2004 Feb 13;998(1):122-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory