About   Help   FAQ
Actc1tm1Buck
Targeted Allele Detail
Nomenclature
Symbol: Actc1tm1Buck
Name: actin, alpha, cardiac muscle 1; targeted mutation 1, Margaret E Buckingham
MGI ID: MGI:3029177
Synonyms: alphac-actinnlaacZ1.1, alphac-actinnlaacZ1.1delta
Gene: Actc1  Location: Chr2:114047282-114052875 bp, - strand  Genetic Position: Chr2, 57.55 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84604
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsSequence encoding nuclear localized lacZ was inserted immediately after the start codon via homologous recombination. A floxed neo cassette included in the targeting vector was excised via cre-mediated recombination. The expression pattern of lacZ recapitulated that of the endogenous gene. (J:84604)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actc1 Mutation:  11 strains or lines available
References
Original:  J:84604 Meilhac SM, et al., A retrospective clonal analysis of the myocardium reveals two phases of clonal growth in the developing mouse heart. Development. 2003 Aug;130(16):3877-89
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/03/2020
MGI 6.15
The Jackson Laboratory