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Rhogtm1Tnr
Targeted Allele Detail
Nomenclature
Symbol: Rhogtm1Tnr
Name: ras homolog family member G; targeted mutation 1, Martin Turner
MGI ID: MGI:3029009
Synonyms: RhoG-, Rhogtm1Evi
Gene: Rhog  Location: Chr7:102239123-102256054 bp, - strand  Genetic Position: Chr7, 54.71 cM, cytoband F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87580
Parent Cell Line:  PC3 (ES Cell)
Strain of Origin:  129S4/SvJae-Tg(Prm-cre)70Og
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 2 which includes the entire open reading frame was replaced with a neomycin resistance gene inserted in reverse orientation. Northern blot analysis confirmed the absence of mRNA transcript. (J:87580)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rhog Mutation:  8 strains or lines available
References
Original:  J:87580 Vigorito E, et al., Immunological function in mice lacking the Rac-related GTPase RhoG. Mol Cell Biol. 2004 Jan;24(2):719-29
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory